LAS VEGAS — Landry Shamet will miss the rest of the NBA Summer League after aggravating a sprained right ankle in the 76ers' loss Friday to the Boston Celtics.

The  rookie guard did not participate in the morning's shootaround for Saturday night's game against the Los Angeles Lakers. Saturday's X-rays were negative.  He will be reevaluated in about three weeks.

This news comes six days after the Sixers announced that second-round pick Shake Melton would miss the summer league with a stress fracture in his back.

It also marks the second straight year that they lost a draft pick in their summer-league opener.  Markelle Fultz sprained his ankle in Vegas on July 8, 2017. He did not play the rest of that summer.

The team has a long history of dealing with rookies, who missed parts of summer-league play due to injuries. The most notable ones were  Fultz, Ben Simmons, Furkan Korkmaz, and Jahlil Okafor. Joel Embiid never played summer-league ball.

Zhaire Smith is the lone Sixers rookie still competing this summer.

The Sixers are off Sunday and will conclude the preliminary round with a game against the Washington Wizards on Monday. The tournament portion of the league starts Wednesday. The championship game is set for July 17.

Shamet aggravated the injury while landing awkwardly late in the second quarter against the Celtics and didn't return to the game. Shamet first injured his ankle during his Sixers predraft workout on June 19.

He had six points on 2-for-5 shooting — all three-pointers — in 12 minutes, 3 seconds before suffering the injury. He also had one assist and one personal foul.

The point guard was selected with the 26th overall pick last month in the NBA draft. The Sixers wanted to see the former Wichita State standout play primarily off the ball. The Sixers already have three point guards in  Simmons, Fultz, and T.J. McConnell on the roster. The thought is that Shamet can come in and make shots while being a secondary ballhandler. On Friday, he was starting to find his groove and get more comfortable as the game progressed.

Shamet left Wichita State after his redshirt sophomore year.  He averaged a team-high 14.9 points and led the American Athletic Conference with 5.2 assists and a 2.5 assist-to-turnover ratio.  He also ranked 13th in NCAA Division I in three-point percentage at 44.2.